Micro-electromechanical Film Bulk Acoustic Sensor for Plasma and Complete Blood Coagulation Monitoring > 자유게시판

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Monitoring blood coagulation is a crucial challenge in the surgeries and the remedy of cardiovascular diseases. In this work, we reported a novel technique for the blood coagulation monitoring based mostly on a micro-electromechanical film bulk acoustic resonator. The resonator was excited by a lateral electric subject and BloodVitals wearable operated underneath the shear mode with a frequency of 1.9GHz. Based on the apparent step-ladder curves of the frequency response to the change of blood viscoelasticity, the coagulation time (prothrombin time) and the coagulation kinetics have been measured with the pattern consumption of solely 1μl. The procoagulant activity of thromboplastin and home SPO2 device the anticoagulant effect of heparin on the blood coagulation process had been illustrated exemplarily. 0.99969 and a consistency with the coefficient of variation less than 5% in contrast with the industrial coagulometer. The proposed film bulk acoustic sensor, which has some great benefits of small measurement, light weight, low cost, simple operation and little pattern consumption, is a promising gadget for BloodVitals device miniaturized, online and automatic analytical system for routine diagnostics of hemostatic standing and BloodVitals SPO2 personal well being monitoring.

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